人 MARCH7 (NM_001282806) cDNA克隆

Accession: NM_001282806
基因名称: MARCH7
基因别名: AXO; AXOT; RNF177; MARCH-VII
基因描述: Homo sapiens membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase (MARCH7), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1908 (查看编码区序列)
翻译后氨基酸长度: 635 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks an alternate in-frame exon in the 5' coding region, and lacks an exon that results in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a.
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G158170 人 MARCH7 (NM_001282806) cDNA克隆 pDONR223 2ug质粒 点击询价

MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Mar 2010]