人 MARCH6 (NM_001270660) cDNA克隆

Accession: NM_001270660
基因名称: MARCH6
基因别名: TEB4; DOA10; RNF176; MARCH-VI
基因描述: Homo sapiens membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase (MARCH6), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2589 (查看编码区序列)
翻译后氨基酸长度: 862 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
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G126629 人 MARCH6 (NM_001270660) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of a family of membrane-associated E3 ubiquitin ligases containing RING-CH-type zinc finger motifs. Ubiquitination of type II deiodinase by the encoded protein is an important regulatory step in thyroid hormone signalling. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]