人 MARCH8 (NM_145021) cDNA克隆

基本信息

Accession: NM_145021
基因名称: MARCH8
基因别名: MIR; c-MIR; RNF178; MARCH-VIII
基因描述: Homo sapiens membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase (MARCH8), transcript variant 2, mRNA.
种属: Human
CDS区长度: 876 (查看编码区序列)
翻译后氨基酸长度: 291 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and lacks an in-frame exon in the 3' coding region, compared to variant 4. This results in a shorter protein (isoform a), compared to isoform b. Variants 2 and 3 encode the same isoform (a).

订购信息

产品编号 产品名称 载体 规格 价格
G109115 人 MARCH8 (NM_145021) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MARCH8 (NM_145021) cDNA克隆 transcript variant 2
人 MARCH8 (NM_001002266) cDNA克隆 transcript variant 3
人 MARCH8 (NM_001282866) cDNA克隆 transcript variant 4

基因简介

MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010]

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