人 PUF60 (NM_001271100) cDNA克隆

基本信息

Accession: NM_001271100
基因名称: PUF60
基因别名: FIR; RoBPI; SIAHBP1
基因描述: Homo sapiens poly-U binding splicing factor 60KDa (PUF60), transcript variant 8, mRNA.
种属: Human
CDS区长度: 1500 (查看编码区序列)
翻译后氨基酸长度: 499 (查看氨基酸序列)
Transcript Variant: This variant (8) differs in the 5' UTR and contains multiple differences in the coding region, compared to variant 1. These differences result in initiation of translation at an alternate in-frame downstream start site. The encoded isoform (h) is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G102245 人 PUF60 (NM_001271100) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PUF60 (NM_078480) cDNA克隆 transcript variant 1
人 PUF60 (NM_014281) cDNA克隆 transcript variant 2
人 PUF60 (NM_001136033) cDNA克隆 transcript variant 3
人 PUF60 (NM_001271096) cDNA克隆 transcript variant 4
人 PUF60 (NM_001271097) cDNA克隆 transcript variant 5
人 PUF60 (NM_001271098) cDNA克隆 transcript variant 6
人 PUF60 (NM_001271099) cDNA克隆 transcript variant 7
人 PUF60 (NM_001271100) cDNA克隆 transcript variant 8

基因简介

This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

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