人 PUF60 (NM_001271096) cDNA克隆

Accession: NM_001271096
基因名称: PUF60
基因别名: FIR; RoBPI; SIAHBP1
基因描述: Homo sapiens poly-U binding splicing factor 60KDa (PUF60), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1626 (查看编码区序列)
翻译后氨基酸长度: 541 (查看氨基酸序列)
Transcript Variant: This variant (4) uses an alternate in-frame splice site and lacks an alternate exon in the coding region, compared to variant 1, but maintains the reading frame. The encoded isoform (d) is shorter than isoform a.
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G102241 人 PUF60 (NM_001271096) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]