人 PUF60 (NM_001136033) cDNA克隆

基本信息

Accession: NM_001136033
基因名称: PUF60
基因别名: FIR; RoBPI; SIAHBP1
基因描述: Homo sapiens poly-U binding splicing factor 60KDa (PUF60), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1551 (查看编码区序列)
翻译后氨基酸长度: 516 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate in-frame downstream start site, compared to variant 1. The encoded isoform (c) has a shorter N-terminus, compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G102238 人 PUF60 (NM_001136033) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PUF60 (NM_078480) cDNA克隆 transcript variant 1
人 PUF60 (NM_014281) cDNA克隆 transcript variant 2
人 PUF60 (NM_001136033) cDNA克隆 transcript variant 3
人 PUF60 (NM_001271096) cDNA克隆 transcript variant 4
人 PUF60 (NM_001271097) cDNA克隆 transcript variant 5
人 PUF60 (NM_001271098) cDNA克隆 transcript variant 6
人 PUF60 (NM_001271099) cDNA克隆 transcript variant 7
人 PUF60 (NM_001271100) cDNA克隆 transcript variant 8

基因简介

This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

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