人 PUF60 (NM_078480) cDNA克隆

Accession: NM_078480
基因名称: PUF60
基因别名: FIR; RoBPI; SIAHBP1
基因描述: Homo sapiens poly-U binding splicing factor 60KDa (PUF60), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1680 (查看编码区序列)
翻译后氨基酸长度: 559 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longest isoform (a).
产品编号 产品名称 载体 规格 价格
G102240 人 PUF60 (NM_078480) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]