人 UBE2L3 (NM_001256356) cDNA克隆

基本信息

Accession: NM_001256356
基因名称: UBE2L3
基因别名: E2-F1; L-UBC; UBCH7; UbcM4
基因描述: Homo sapiens ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 3, mRNA.
种属: Human
CDS区长度: 369 (查看编码区序列)
翻译后氨基酸长度: 122 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate 5' splice site, lacks an alternate exon, and initiates translation from a downstream start site, compared to variant 4. It encodes a shorter and distinct N-terminus in isoform 3, compared to isoform 4.

订购信息

产品编号 产品名称 载体 规格 价格
G163311 人 UBE2L3 (NM_001256356) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 UBE2L3 (NM_003347) cDNA克隆 transcript variant 1
人 UBE2L3 (NM_001256356) cDNA克隆 transcript variant 3
人 UBE2L3 (NM_001256355) cDNA克隆 transcript variant 4

基因简介

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]

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