人 UBE2L3 (NM_001256355) cDNA克隆

Accession: NM_001256355
基因名称: UBE2L3
基因别名: E2-F1; L-UBC; UBCH7; UbcM4
基因描述: Homo sapiens ubiquitin-conjugating enzyme E2L 3 (UBE2L3), transcript variant 4, mRNA.
种属: Human
CDS区长度: 639 (查看编码区序列)
翻译后氨基酸长度: 212 (查看氨基酸序列)
Transcript Variant: This variant (4) encodes the longest isoform (4).
产品编号 产品名称 载体 规格 价格
G163310 人 UBE2L3 (NM_001256355) cDNA克隆 pDONR223 2ug质粒 点击询价

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]