人 BCL11B (NM_001282237) cDNA克隆

Accession: NM_001282237
基因名称: BCL11B
基因别名: ATL1; RIT1; CTIP2; CTIP-2; ZNF856B; ATL1-beta; ATL1-alpha; ATL1-delta; ATL1-gamma; hRIT1-alpha
基因描述: Homo sapiens B-cell CLL/lymphoma 11B (zinc finger protein) (BCL11B), transcript variant 3, mRNA.
种属: Human
CDS区长度: 2682 (查看编码区序列)
翻译后氨基酸长度: 893 (查看氨基酸序列)
Transcript Variant: This variant (3) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is 1 aa shorter compared to isoform 1.
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G158196 人 BCL11B (NM_001282237) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]