人 BCL2 (NM_000657) cDNA克隆

基本信息

Accession: NM_000657
基因名称: BCL2
基因别名: Bcl-2; PPP1R50
基因描述: Homo sapiens B-cell CLL/lymphoma 2 (BCL2), transcript variant beta, mRNA.
种属: Human
CDS区长度: 618 (查看编码区序列)
翻译后氨基酸长度: 205 (查看氨基酸序列)
Transcript Variant: This variant (beta) differs in the 3' UTR and coding region compared to variant alpha. The resulting isoform (beta) is shorter and has a distinct C-terminus compared to isoform alpha.

订购信息

产品编号 产品名称 载体 规格 价格
G157086 人 BCL2 (NM_000657) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 BCL2 (NM_000633) cDNA克隆 transcript variant alpha
人 BCL2 (NM_000657) cDNA克隆 transcript variant beta

基因简介

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008]

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