人 PCSK2 (NM_001201529) cDNA克隆

基本信息

Accession: NM_001201529
基因名称: PCSK2
基因别名: PC2; NEC2; SPC2; NEC 2; NEC-2
基因描述: Homo sapiens proprotein convertase subtilisin/kexin type 2 (PCSK2), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1812 (查看编码区序列)
翻译后氨基酸长度: 603 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an exon in the 5' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G153895 人 PCSK2 (NM_001201529) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PCSK2 (NM_002594) cDNA克隆 transcript variant 1
人 PCSK2 (NM_001201529) cDNA克隆 transcript variant 2
人 PCSK2 (NM_001201528) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

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