人 PCSK2 (NM_001201528) cDNA克隆

基本信息

Accession: NM_001201528
基因名称: PCSK2
基因别名: PC2; NEC2; SPC2; NEC 2; NEC-2
基因描述: Homo sapiens proprotein convertase subtilisin/kexin type 2 (PCSK2), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1860 (查看编码区序列)
翻译后氨基酸长度: 619 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and uses an in-frame downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G153894 人 PCSK2 (NM_001201528) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PCSK2 (NM_002594) cDNA克隆 transcript variant 1
人 PCSK2 (NM_001201529) cDNA克隆 transcript variant 2
人 PCSK2 (NM_001201528) cDNA克隆 transcript variant 3

基因简介

This gene encodes a member of the subtilisin-like proprotein convertase family. These enzymes process latent precursor proteins into their biologically active products. The encoded protein plays a critical role in hormone biosynthesis by processing a variety of prohormones including proinsulin, proopiomelanocortin and proluteinizing-hormone-releasing hormone. Single nucleotide polymorphisms in this gene may increase susceptibility to myocardial infarction and type 2 diabetes. This gene may also play a role in tumor development and progression. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

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