人 PCSK5 (NM_006200) cDNA克隆

Accession: NM_006200
基因名称: PCSK5
基因别名: PC5; PC6; PC6A; SPC6; subtilase
基因描述: Homo sapiens proprotein convertase subtilisin/kexin type 5 (PCSK5), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2742 (查看编码区序列)
翻译后氨基酸长度: 913 (查看氨基酸序列)
Transcript Variant: This variant (2) represents use of an alternate 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a substantially shorter and distinct C-terminus, compared to isoform 1.
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G104538 人 PCSK5 (NM_006200) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]