人 PCSK6 (NM_138325) cDNA克隆

Accession: NM_138325
基因名称: PCSK6
基因别名: SPC4; PACE4
基因描述: Homo sapiens proprotein convertase subtilisin/kexin type 6 (PCSK6), transcript variant 6, mRNA.
种属: Human
CDS区长度: 1995 (查看编码区序列)
翻译后氨基酸长度: 664 (查看氨基酸序列)
Transcript Variant: This variant (6) lacks nine 3' exons and uses an alternate 3' terminal exon, compared to variant 1, resulting in a shorter isoform (f) with a unique C-terminus, compared to isoform a.
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G153585 人 PCSK6 (NM_138325) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]