人 ITGB7 (NM_000889) cDNA克隆

Accession: NM_000889
基因名称: ITGB7
基因描述: Homo sapiens integrin, beta 7 (ITGB7), transcript variant 1, mRNA.
种属: Human
CDS区长度: 2397 (查看编码区序列)
翻译后氨基酸长度: 798 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript.
产品编号 产品名称 载体 规格 价格
G150943 人 ITGB7 (NM_000889) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]