人 ITGB6 (NM_001282388) cDNA克隆

基本信息

Accession: NM_001282388
基因名称: ITGB6
基因描述: Homo sapiens integrin, beta 6 (ITGB6), transcript variant 5, mRNA.
种属: Human
CDS区长度: 2241 (查看编码区序列)
翻译后氨基酸长度: 746 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks an alternate 5' exon, compared to variant 1. This variant represents translation initiation at a downstream AUG compared to variant 1; the 5'-most initiation codon, as used in variant 1, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the downstream AUG resulting in a shorter isoform (d) with a distinct N-terminus, compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G124998 人 ITGB6 (NM_001282388) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 ITGB6 (NM_000888) cDNA克隆 transcript variant 1
人 ITGB6 (NM_001282353) cDNA克隆 transcript variant 2
人 ITGB6 (NM_001282354) cDNA克隆 transcript variant 3
人 ITGB6 (NM_001282355) cDNA克隆 transcript variant 4
人 ITGB6 (NM_001282388) cDNA克隆 transcript variant 5
人 ITGB6 (NM_001282389) cDNA克隆 transcript variant 6
人 ITGB6 (NM_001282390) cDNA克隆 transcript variant 7

基因简介

This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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