人 DNMT1 (NM_001379) cDNA克隆

Accession: NM_001379
基因名称: DNMT1
基因别名: AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN
基因描述: Homo sapiens DNA (cytosine-5-)-methyltransferase 1 (DNMT1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 4851 (查看编码区序列)
翻译后氨基酸长度: 1616 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
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G134221 人 DNMT1 (NM_001379) cDNA克隆 pDONR223 2ug质粒 点击询价

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]