小鼠 Dnmt3a (NM_153743) cDNA克隆

Accession: NM_153743
基因名称: Dnmt3a
基因别名: MmuIIIA
基因描述: Mus musculus DNA methyltransferase 3A (Dnmt3a), transcript variant 2, mRNA.
种属: Mouse
CDS区长度: 2070 (查看编码区序列)
翻译后氨基酸长度: 689 (查看氨基酸序列)
Transcript Variant: This variant (2) represents use of an alternate promoter, compared to variant 1. It differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream in-frame start codon. The encoded isoform (2, also known as Dnmt3a2) has a shorter N-terminus, compared to isoform 1.
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G130486 小鼠 Dnmt3a (NM_153743) cDNA克隆 pDONR223 2ug质粒 点击询价

This is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Loss of function of this gene causes developmental defects in multiple different organ systems. There is a pseudogene for this gene located on chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Nov 2012]