人 DNMT3A (NM_153759) cDNA克隆

基本信息

Accession: NM_153759
基因名称: DNMT3A
基因别名: DNMT3A2; M.HsaIIIA
基因描述: Homo sapiens DNA (cytosine-5-)-methyltransferase 3 alpha (DNMT3A), transcript variant 2, mRNA.
种属: Human
CDS区长度: 2172 (查看编码区序列)
翻译后氨基酸长度: 723 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR and 5' coding region but maintains the reading frame, compared to variant 1. Variant 2 encodes isoform b, which has a distinct N-terminus compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G117098 人 DNMT3A (NM_153759) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 DNMT3A (NM_175629) cDNA克隆 transcript variant 1
人 DNMT3A (NM_153759) cDNA克隆 transcript variant 2
人 DNMT3A (NM_022552) cDNA克隆 transcript variant 3
人 DNMT3A (NM_175630) cDNA克隆 transcript variant 4

基因简介

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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