小鼠 Dnmt3b (NM_001271747) cDNA克隆

基本信息

Accession: NM_001271747
基因名称: Dnmt3b
基因别名: MmuIIIB
基因描述: Mus musculus DNA methyltransferase 3B (Dnmt3b), transcript variant 9, mRNA.
种属: Mouse
CDS区长度: 2331 (查看编码区序列)
翻译后氨基酸长度: 776 (查看氨基酸序列)
Transcript Variant: This variant (9) contains multiple differences in the coding region, but maintains the reading frame, compared to variant 5. The encoded isoform (3, also known as Dnmt3b3) is shorter than isoform 5. Variants 3 and 9 encode the same isoform (3).

订购信息

产品编号 产品名称 载体 规格 价格
G130495 小鼠 Dnmt3b (NM_001271747) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

小鼠 Dnmt3b (NM_001003961) cDNA克隆 transcript variant 1
小鼠 Dnmt3b (NM_001003960) cDNA克隆 transcript variant 2
小鼠 Dnmt3b (NM_010068) cDNA克隆 transcript variant 3
小鼠 Dnmt3b (NM_001003963) cDNA克隆 transcript variant 4
小鼠 Dnmt3b (NM_001122997) cDNA克隆 transcript variant 5
小鼠 Dnmt3b (NM_001271744) cDNA克隆 transcript variant 6
小鼠 Dnmt3b (NM_001271745) cDNA克隆 transcript variant 7
小鼠 Dnmt3b (NM_001271746) cDNA克隆 transcript variant 8
小鼠 Dnmt3b (NM_001271747) cDNA克隆 transcript variant 9

基因简介

This is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Loss of function of this gene results in severe developmental defects and loss of viability. Mutation of the related gene in humans causes immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. There is a pseudogene for this gene located adjacent to this gene in the same region of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Nov 2012]

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