人 FLT3LG (NM_001278638) cDNA克隆

基本信息

Accession: NM_001278638
基因名称: FLT3LG
基因别名: FL; FLT3L
基因描述: Homo sapiens fms-related tyrosine kinase 3 ligand (FLT3LG), transcript variant 5, mRNA.
种属: Human
CDS区长度: 462 (查看编码区序列)
翻译后氨基酸长度: 153 (查看氨基酸序列)
Transcript Variant: This variant (5) uses an alternate splice site in the 5' UTR which results in the use of a downstream AUG compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1. Variants 4 and 5 encode the same isoform (2).

订购信息

产品编号 产品名称 载体 规格 价格
G125468 人 FLT3LG (NM_001278638) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 FLT3LG (NM_001204502) cDNA克隆 transcript variant 1
人 FLT3LG (NM_001204503) cDNA克隆 transcript variant 2
人 FLT3LG (NM_001459) cDNA克隆 transcript variant 3
人 FLT3LG (NM_001278637) cDNA克隆 transcript variant 4
人 FLT3LG (NM_001278638) cDNA克隆 transcript variant 5

基因简介

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]

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