人 FLT3LG (NM_001459) cDNA克隆

Accession: NM_001459
基因名称: FLT3LG
基因别名: FL; FLT3L
基因描述: Homo sapiens fms-related tyrosine kinase 3 ligand (FLT3LG), transcript variant 3, mRNA.
种属: Human
CDS区长度: 708 (查看编码区序列)
翻译后氨基酸长度: 235 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 encode the same isoform (1).
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G125464 人 FLT3LG (NM_001459) cDNA克隆 pDONR223 2ug质粒 点击询价

Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]