The protein encoded by this gene is a calcium-permeable cation channel that is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Several alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Jul 2008]
人 TRPM2 (NM_003307) cDNA克隆
| Accession: | NM_003307 |
|---|---|
| 基因名称: | TRPM2 |
| 基因别名: | KNP3; EREG1; TRPC7; LTRPC2; NUDT9H; NUDT9L1 |
| 基因描述: | Homo sapiens transient receptor potential cation channel, subfamily M, member 2 (TRPM2), transcript variant 1, mRNA. |
| 种属: | Human |
| CDS区长度: | 4512 (查看编码区序列) |
| 翻译后氨基酸长度: | 1503 (查看氨基酸序列) |
| Transcript Variant: | This variant (1) is the protein-coding variant. |
| 人 TRPM2 (NM_003307) cDNA克隆 | transcript variant 1 |
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