人 TRPM1 (NM_001252020) cDNA克隆

基本信息

Accession: NM_001252020
基因名称: TRPM1
基因别名: MLSN1; CSNB1C; LTRPC1
基因描述: Homo sapiens transient receptor potential cation channel, subfamily M, member 1 (TRPM1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 4929 (查看编码区序列)
翻译后氨基酸长度: 1642 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

订购信息

产品编号 产品名称 载体 规格 价格
G120439 人 TRPM1 (NM_001252020) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TRPM1 (NM_001252020) cDNA克隆 transcript variant 1
人 TRPM1 (NM_002420) cDNA克隆 transcript variant 2
人 TRPM1 (NM_001252024) cDNA克隆 transcript variant 3
人 TRPM1 (NM_001252030) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]

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