人 TRPM1 (NM_001252024) cDNA克隆

基本信息

Accession: NM_001252024
基因名称: TRPM1
基因别名: MLSN1; CSNB1C; LTRPC1
基因描述: Homo sapiens transient receptor potential cation channel, subfamily M, member 1 (TRPM1), transcript variant 3, mRNA.
种属: Human
CDS区长度: 4878 (查看编码区序列)
翻译后氨基酸长度: 1625 (查看氨基酸序列)
Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate exon in the 5' coding region. These differences cause translation initiation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G120440 人 TRPM1 (NM_001252024) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 TRPM1 (NM_001252020) cDNA克隆 transcript variant 1
人 TRPM1 (NM_002420) cDNA克隆 transcript variant 2
人 TRPM1 (NM_001252024) cDNA克隆 transcript variant 3
人 TRPM1 (NM_001252030) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]

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