人 PLCB4 (NM_000933) cDNA克隆

Accession: NM_000933
基因名称: PLCB4
基因别名: ARCND2; PI-PLC
基因描述: Homo sapiens phospholipase C, beta 4 (PLCB4), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3585 (查看编码区序列)
翻译后氨基酸长度: 1194 (查看氨基酸序列)
Transcript Variant: This variant (1) lacks an alternate in-frame exon in the central coding region and includes an alternate exon in the 3' coding region that results in a frameshift, compared to variant 3. The complete exon combination of the 5' UTR for this variant has not been determined. The resulting isoform (a) lacks an internal segment and has a longer and distinct C-terminus, compared to isoform c.
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G124734 人 PLCB4 (NM_000933) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals in the retina. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2010]