人 PLCB1 (NM_015192) cDNA克隆

Accession: NM_015192
基因名称: PLCB1
基因别名: PLC-I; EIEE12; PI-PLC; PLC154; PLCB1A; PLCB1B; PLC-154
基因描述: Homo sapiens phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 3651 (查看编码区序列)
翻译后氨基酸长度: 1216 (查看氨基酸序列)
Transcript Variant: This variant (1) encodes the longer isoform (a).
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G121129 人 PLCB1 (NM_015192) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]