人 PLCB1 (NM_182734) cDNA克隆

Accession: NM_182734
基因名称: PLCB1
基因别名: PLC-I; EIEE12; PI-PLC; PLC154; PLCB1A; PLCB1B; PLC-154
基因描述: Homo sapiens phospholipase C, beta 1 (phosphoinositide-specific) (PLCB1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 3522 (查看编码区序列)
翻译后氨基酸长度: 1173 (查看氨基酸序列)
Transcript Variant: This variant (2) includes an alternate exon in the 3' end compared to variant 1. This exon contains an in-frame stop codon, and the resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a.
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G121128 人 PLCB1 (NM_182734) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]