人 EYA3 (NM_001282562) cDNA克隆

基本信息

Accession: NM_001282562
基因名称: EYA3
基因描述: Homo sapiens eyes absent homolog 3 (Drosophila) (EYA3), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1563 (查看编码区序列)
翻译后氨基酸长度: 520 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks an alternate exon in the 5' region which results in the use of a downstream in-frame start codon, compared to variant 1. The encoded isoform (d) is shorter at the N-terminus, compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G116249 人 EYA3 (NM_001282562) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 EYA3 (NM_001990) cDNA克隆 transcript variant 1
人 EYA3 (NM_001282560) cDNA克隆 transcript variant 2
人 EYA3 (NM_001282561) cDNA克隆 transcript variant 3
人 EYA3 (NM_001282562) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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