人 EYA3 (NM_001282560) cDNA克隆

基本信息

Accession: NM_001282560
基因名称: EYA3
基因描述: Homo sapiens eyes absent homolog 3 (Drosophila) (EYA3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1611 (查看编码区序列)
翻译后氨基酸长度: 536 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon in the central coding region, and contains an alternate 3' terminal exon and thus differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (b) has a distinct C-terminus and is shorter than isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G116247 人 EYA3 (NM_001282560) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 EYA3 (NM_001990) cDNA克隆 transcript variant 1
人 EYA3 (NM_001282560) cDNA克隆 transcript variant 2
人 EYA3 (NM_001282561) cDNA克隆 transcript variant 3
人 EYA3 (NM_001282562) cDNA克隆 transcript variant 4

基因简介

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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