人 EYA3 (NM_001282561) cDNA克隆

Accession: NM_001282561
基因名称: EYA3
基因描述: Homo sapiens eyes absent homolog 3 (Drosophila) (EYA3), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1584 (查看编码区序列)
翻译后氨基酸长度: 527 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (c) that is shorter than isoform a.
产品编号 产品名称 载体 规格 价格
G116248 人 EYA3 (NM_001282561) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013]