人 IRAK3 (NM_007199) cDNA克隆

Accession: NM_007199
基因名称: IRAK3
基因别名: ASRT5; IRAKM
基因描述: Homo sapiens interleukin-1 receptor-associated kinase 3 (IRAK3), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1791 (查看编码区序列)
翻译后氨基酸长度: 596 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
产品编号 产品名称 载体 规格 价格
G115678 人 IRAK3 (NM_007199) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]