人 IRAK4 (NM_016123) cDNA克隆

基本信息

Accession: NM_016123
基因名称: IRAK4
基因别名: IPD1; REN64; IRAK-4; NY-REN-64
基因描述: Homo sapiens interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1383 (查看编码区序列)
翻译后氨基酸长度: 460 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).

订购信息

产品编号 产品名称 载体 规格 价格
G106771 人 IRAK4 (NM_016123) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IRAK4 (NM_001114182) cDNA克隆 transcript variant 1
人 IRAK4 (NM_016123) cDNA克隆 transcript variant 2
人 IRAK4 (NM_001145256) cDNA克隆 transcript variant 3
人 IRAK4 (NM_001145257) cDNA克隆 transcript variant 4
人 IRAK4 (NM_001145258) cDNA克隆 transcript variant 5

基因简介

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

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