人 IRAK3 (NM_001142523) cDNA克隆

基本信息

Accession: NM_001142523
基因名称: IRAK3
基因别名: ASRT5; IRAKM
基因描述: Homo sapiens interleukin-1 receptor-associated kinase 3 (IRAK3), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1608 (查看编码区序列)
翻译后氨基酸长度: 535 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform b), compared to isoform a.

订购信息

产品编号 产品名称 载体 规格 价格
G115677 人 IRAK3 (NM_001142523) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 IRAK3 (NM_007199) cDNA克隆 transcript variant 1
人 IRAK3 (NM_001142523) cDNA克隆 transcript variant 2

基因简介

This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

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