人 CDC23 (NM_004661) cDNA克隆

Accession: NM_004661
基因名称: CDC23
基因别名: APC8; CUT23; ANAPC8
基因描述: Homo sapiens cell division cycle 23 (CDC23), mRNA.
种属: Human
CDS区长度: 1794 (查看编码区序列)
翻译后氨基酸长度: 597 (查看氨基酸序列)
产品编号 产品名称 载体 规格 价格
G115293 人 CDC23 (NM_004661) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008]