人 CDC45 (NM_001178011) cDNA克隆

基本信息

Accession: NM_001178011
基因名称: CDC45
基因别名: CDC45L; CDC45L2; PORC-PI-1
基因描述: Homo sapiens cell division cycle 45 (CDC45), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1563 (查看编码区序列)
翻译后氨基酸长度: 520 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks two in-frame exons in the CDS, compared to variant 1. The resulting isoform (3) is shorter than isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G112308 人 CDC45 (NM_001178011) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 CDC45 (NM_001178010) cDNA克隆 transcript variant 1
人 CDC45 (NM_003504) cDNA克隆 transcript variant 2
人 CDC45 (NM_001178011) cDNA克隆 transcript variant 3

基因简介

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

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