人 CDC25A (NM_001789) cDNA克隆

Accession: NM_001789
基因名称: CDC25A
基因别名: CDC25A2
基因描述: Homo sapiens cell division cycle 25A (CDC25A), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1575 (查看编码区序列)
翻译后氨基酸长度: 524 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
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G112005 人 CDC25A (NM_001789) cDNA克隆 pDONR223 2ug质粒 点击询价

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]