人 PVR (NM_006505) cDNA克隆

Accession: NM_006505
基因名称: PVR
基因别名: PVS; HVED; CD155; NECL5; TAGE4; Necl-5
基因描述: Homo sapiens poliovirus receptor (PVR), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1254 (查看编码区序列)
翻译后氨基酸长度: 417 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (alpha), also known as H20A.
产品编号 产品名称 载体 规格 价格
G110842 人 PVR (NM_006505) cDNA克隆 pDONR223 2ug质粒 点击询价

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]