人 PVR (NM_001135769) cDNA克隆

基本信息

Accession: NM_001135769
基因名称: PVR
基因别名: PVS; HVED; CD155; NECL5; TAGE4; Necl-5
基因描述: Homo sapiens poliovirus receptor (PVR), transcript variant 3, mRNA.
种属: Human
CDS区长度: 1095 (查看编码区序列)
翻译后氨基酸长度: 364 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (gamma) lacks an internal segment including the putative transmembrane domain, compared to isoform alpha, resulting in its secretion into serum and cerebrospinal fluid.

订购信息

产品编号 产品名称 载体 规格 价格
G110840 人 PVR (NM_001135769) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PVR (NM_006505) cDNA克隆 transcript variant 1
人 PVR (NM_001135768) cDNA克隆 transcript variant 2
人 PVR (NM_001135769) cDNA克隆 transcript variant 3
人 PVR (NM_001135770) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

相关产品