人 PVR (NM_001135770) cDNA克隆

基本信息

Accession: NM_001135770
基因名称: PVR
基因别名: PVS; HVED; CD155; NECL5; TAGE4; Necl-5
基因描述: Homo sapiens poliovirus receptor (PVR), transcript variant 4, mRNA.
种属: Human
CDS区长度: 1179 (查看编码区序列)
翻译后氨基酸长度: 392 (查看氨基酸序列)
Transcript Variant: This variant (4) has an alternate 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (delta), also known as H20B, has a shorter and distinct C-terminus, compared to isoform alpha.

订购信息

产品编号 产品名称 载体 规格 价格
G110841 人 PVR (NM_001135770) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 PVR (NM_006505) cDNA克隆 transcript variant 1
人 PVR (NM_001135768) cDNA克隆 transcript variant 2
人 PVR (NM_001135769) cDNA克隆 transcript variant 3
人 PVR (NM_001135770) cDNA克隆 transcript variant 4

基因简介

The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

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