人 QTRTD1 (NM_001256837) cDNA克隆

Accession: NM_001256837
基因名称: QTRTD1
基因描述: Homo sapiens queuine tRNA-ribosyltransferase domain containing 1 (QTRTD1), transcript variant 4, mRNA.
种属: Human
CDS区长度: 879 (查看编码区序列)
翻译后氨基酸长度: 292 (查看氨基酸序列)
Transcript Variant: This variant (4) lacks two internal exons, uses an alternate splice site and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (4) has a shorter N-terminus, compared to isoform 1.
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G110825 人 QTRTD1 (NM_001256837) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]