人 QTRTD1 (NM_001256835) cDNA克隆

Accession: NM_001256835
基因名称: QTRTD1
基因描述: Homo sapiens queuine tRNA-ribosyltransferase domain containing 1 (QTRTD1), transcript variant 2, mRNA.
种属: Human
CDS区长度: 1284 (查看编码区序列)
翻译后氨基酸长度: 427 (查看氨基酸序列)
Transcript Variant: This variant (2) lacks an internal exon in the 5' region and initiates translation at an upstream start codon, compared to variant 1. The encoded isoform (2) is longer and has a distinct N-terminus, compared to isoform 1.
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G110823 人 QTRTD1 (NM_001256835) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]