人 QTRTD1 (NM_024638) cDNA克隆

Accession: NM_024638
基因名称: QTRTD1
基因描述: Homo sapiens queuine tRNA-ribosyltransferase domain containing 1 (QTRTD1), transcript variant 1, mRNA.
种属: Human
CDS区长度: 1248 (查看编码区序列)
翻译后氨基酸长度: 415 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes isoform 1.
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G110822 人 QTRTD1 (NM_024638) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]