人 MGLL (NM_001256585) cDNA克隆

Accession: NM_001256585
基因名称: MGLL
基因别名: MGL; HUK5; MAGL; HU-K5
基因描述: Homo sapiens monoglyceride lipase (MGLL), transcript variant 3, mRNA.
种属: Human
CDS区长度: 852 (查看编码区序列)
翻译后氨基酸长度: 283 (查看氨基酸序列)
Transcript Variant: This variant (3) lacks an exon in the 3' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
产品编号 产品名称 载体 规格 价格
G109571 人 MGLL (NM_001256585) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]