人 MGLL (NM_001003794) cDNA克隆

基本信息

Accession: NM_001003794
基因名称: MGLL
基因别名: MGL; HUK5; MAGL; HU-K5
基因描述: Homo sapiens monoglyceride lipase (MGLL), transcript variant 2, mRNA.
种属: Human
CDS区长度: 912 (查看编码区序列)
翻译后氨基酸长度: 303 (查看氨基酸序列)
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G109569 人 MGLL (NM_001003794) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 MGLL (NM_007283) cDNA克隆 transcript variant 1
人 MGLL (NM_001003794) cDNA克隆 transcript variant 2
人 MGLL (NM_001256585) cDNA克隆 transcript variant 3

基因简介

This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]

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