人 MGLL (NM_007283) cDNA克隆

Accession: NM_007283
基因名称: MGLL
基因别名: MGL; HUK5; MAGL; HU-K5
基因描述: Homo sapiens monoglyceride lipase (MGLL), transcript variant 1, mRNA.
种属: Human
CDS区长度: 942 (查看编码区序列)
翻译后氨基酸长度: 313 (查看氨基酸序列)
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
产品编号 产品名称 载体 规格 价格
G109570 人 MGLL (NM_007283) cDNA克隆 pDONR223 2ug质粒 点击询价

This gene encodes a serine hydrolase of the AB hydrolase superfamily that catalyzes the conversion of monoacylglycerides to free fatty acids and glycerol. The encoded protein plays a critical role in several physiological processes including pain and nociperception through hydrolysis of the endocannabinoid 2-arachidonoylglycerol. Expression of this gene may play a role in cancer tumorigenesis and metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2012]