人 BCL2L12 (NM_001282517) cDNA克隆

基本信息

Accession: NM_001282517
基因名称: BCL2L12
基因描述: Homo sapiens BCL2-like 12 (proline rich) (BCL2L12), transcript variant 5, mRNA.
种属: Human
CDS区长度: 531 (查看编码区序列)
翻译后氨基酸长度: 176 (查看氨基酸序列)
Transcript Variant: This variant (5) lacks two coding exons, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.

订购信息

产品编号 产品名称 载体 规格 价格
G103654 人 BCL2L12 (NM_001282517) cDNA克隆 pDONR223 2ug质粒 点击询价

载体信息

pDONR223载体图谱

相关转录本

人 BCL2L12 (NM_138639) cDNA克隆 transcript variant 1
人 BCL2L12 (NM_001282520) cDNA克隆 transcript variant 10
人 BCL2L12 (NM_001282521) cDNA克隆 transcript variant 12
人 BCL2L12 (NM_001040668) cDNA克隆 transcript variant 3
人 BCL2L12 (NM_001282516) cDNA克隆 transcript variant 4
人 BCL2L12 (NM_001282517) cDNA克隆 transcript variant 5
人 BCL2L12 (NM_001282519) cDNA克隆 transcript variant 8

基因简介

This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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