binds the promoter of the Na+/H+ exchanger NHE1 and mediates thyroid hormone induced transcriptional activation [RGD, Feb 2006]
Accession: | NM_001017960 |
---|---|
基因名称: | Thra |
基因别名: | ERBA1; Thra1; c-erbA-1 |
基因描述: | Rattus norvegicus thyroid hormone receptor alpha (Thra), transcript variant TRalpha1, mRNA. |
种属: | Rat |
CDS区长度: | 1233 (查看编码区序列) |
翻译后氨基酸长度: | 410 (查看氨基酸序列) |
Transcript Variant: | This variant (TRalpha1) differs in the 3' UTR and coding region compared to TRalpha2, resulting in a shorter isoform (TRalpha1) with a distinct C-terminus. The TRalpha1 isoform, also known as c-erbAalpha1, functions as a thyroid hormone-dependent transcription factor. |
大鼠 Thra (NM_001017960) cDNA克隆 | transcript variant TRalpha1 |
大鼠 Thra (NM_031134) cDNA克隆 | transcript variant TRalpha2 |
binds the promoter of the Na+/H+ exchanger NHE1 and mediates thyroid hormone induced transcriptional activation [RGD, Feb 2006]