binds the promoter of the Na+/H+ exchanger NHE1 and mediates thyroid hormone induced transcriptional activation [RGD, Feb 2006]
Accession: | NM_031134 |
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基因名称: | Thra |
基因别名: | ERBA1; Thra1; c-erbA-1 |
基因描述: | Rattus norvegicus thyroid hormone receptor alpha (Thra), transcript variant TRalpha2, mRNA. |
种属: | Rat |
CDS区长度: | 1479 (查看编码区序列) |
翻译后氨基酸长度: | 492 (查看氨基酸序列) |
Transcript Variant: | This variant (TRalpha2) contains an alternate 3' terminal exon compared to variant TRalpha1. The resulting protein (c-erbAalpha2, also known as TRalpha 2) has a distinct C-terminus compared to isoform TRalpha1, and fails to bind thyroid hormones or to trans-activate thyroid hormone responsive genes. |
大鼠 Thra (NM_001017960) cDNA克隆 | transcript variant TRalpha1 |
大鼠 Thra (NM_031134) cDNA克隆 | transcript variant TRalpha2 |
binds the promoter of the Na+/H+ exchanger NHE1 and mediates thyroid hormone induced transcriptional activation [RGD, Feb 2006]